WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_AACTTT_UNKNOWN       ID:DB_ID:1851
C=1859; O=28; E=5.60; R=5.00; rawP=1.49e-12; adjP=4.75e-10
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000092445 NA TYRO3 TYRO3 protein tyrosine kinase 7301 ENSG00000092445
2  ENSG00000158571 NA PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 5207 ENSG00000158571
3  ENSG00000105926 NA MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) 51678 ENSG00000105926
4  ENSG00000070193 NA FGF10 fibroblast growth factor 10 2255 ENSG00000070193
5  ENSG00000123612 NA ACVR1C activin A receptor, type IC 130399 ENSG00000123612
6  ENSG00000076716 NA GPC4 glypican 4 2239 ENSG00000076716
7  ENSG00000184811 NA TUSC5 tumor suppressor candidate 5 286753 ENSG00000184811
8  ENSG00000172137 NA CALB2 calbindin 2 794 ENSG00000172137
9  ENSG00000122756 NA CNTFR ciliary neurotrophic factor receptor 1271 ENSG00000122756
10  ENSG00000132854 NA KANK4 KN motif and ankyrin repeat domains 4 163782 ENSG00000132854
11  ENSG00000186642 NA PDE2A phosphodiesterase 2A, cGMP-stimulated 5138 ENSG00000186642
12  ENSG00000176463 NA SLCO3A1 solute carrier organic anion transporter family, member 3A1 28232 ENSG00000176463
13  ENSG00000008394 NA MGST1 microsomal glutathione S-transferase 1 4257 ENSG00000008394
14  ENSG00000142949 NA PTPRF protein tyrosine phosphatase, receptor type, F 5792 ENSG00000142949
15  ENSG00000152822 NA GRM1 glutamate receptor, metabotropic 1 2911 ENSG00000152822
16  ENSG00000168490 NA PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 9796 ENSG00000168490
17  ENSG00000131771 NA PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 84152 ENSG00000131771
18  ENSG00000175426 NA PCSK1 proprotein convertase subtilisin/kexin type 1 5122 ENSG00000175426
19  ENSG00000188517 NA COL25A1 collagen, type XXV, alpha 1 84570 ENSG00000188517
20  ENSG00000101856 NA PGRMC1 progesterone receptor membrane component 1 10857 ENSG00000101856
21  ENSG00000135116 NA HRK harakiri, BCL2 interacting protein (contains only BH3 domain) 8739 ENSG00000135116
22  ENSG00000136895 NA GARNL3 GTPase activating Rap/RanGAP domain-like 3 84253 ENSG00000136895
23  ENSG00000006128 NA TAC1 tachykinin, precursor 1 6863 ENSG00000006128
24  ENSG00000143867 NA OSR1 odd-skipped related 1 (Drosophila) 130497 ENSG00000143867
25  ENSG00000135333 NA EPHA7 EPH receptor A7 2045 ENSG00000135333
26  ENSG00000166819 NA PLIN1 perilipin 1 5346 ENSG00000166819
27  ENSG00000112559 NA MDFI MyoD family inhibitor 4188 ENSG00000112559
28  ENSG00000170323 NA FABP4 fatty acid binding protein 4, adipocyte 2167 ENSG00000170323


Database:Transcription Target       Name:hsa_GGGAGGRR_V$MAZ_Q6       ID:DB_ID:2430
C=2250; O=25; E=6.78; R=3.69; rawP=1.42e-08; adjP=2.26e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000132170 NA PPARG peroxisome proliferator-activated receptor gamma 5468 ENSG00000132170
2  ENSG00000145423 NA SFRP2 secreted frizzled-related protein 2 6423 ENSG00000145423
3  ENSG00000076716 NA GPC4 glypican 4 2239 ENSG00000076716
4  ENSG00000172901 NA AQPEP laeverin 206338 ENSG00000172901
5  ENSG00000122756 NA CNTFR ciliary neurotrophic factor receptor 1271 ENSG00000122756
6  ENSG00000099194 NA SCD stearoyl-CoA desaturase (delta-9-desaturase) 6319 ENSG00000099194
7  ENSG00000186642 NA PDE2A phosphodiesterase 2A, cGMP-stimulated 5138 ENSG00000186642
8  ENSG00000120875 NA DUSP4 dual specificity phosphatase 4 1846 ENSG00000120875
9  ENSG00000092621 NA PHGDH phosphoglycerate dehydrogenase 26227 ENSG00000092621
10  ENSG00000142949 NA PTPRF protein tyrosine phosphatase, receptor type, F 5792 ENSG00000142949
11  ENSG00000138207 NA RBP4 retinol binding protein 4, plasma 5950 ENSG00000138207
12  ENSG00000152822 NA GRM1 glutamate receptor, metabotropic 1 2911 ENSG00000152822
13  ENSG00000168490 NA PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 9796 ENSG00000168490
14  ENSG00000188517 NA COL25A1 collagen, type XXV, alpha 1 84570 ENSG00000188517
15  ENSG00000135144 NA DTX1 deltex homolog 1 (Drosophila) 1840 ENSG00000135144
16  ENSG00000145824 NA CXCL14 chemokine (C-X-C motif) ligand 14 9547 ENSG00000145824
17  ENSG00000079435 NA LIPE lipase, hormone-sensitive 3991 ENSG00000079435
18  ENSG00000130876 NA SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 56301 ENSG00000130876
19  ENSG00000135116 NA HRK harakiri, BCL2 interacting protein (contains only BH3 domain) 8739 ENSG00000135116
20  ENSG00000006128 NA TAC1 tachykinin, precursor 1 6863 ENSG00000006128
21  ENSG00000135333 NA EPHA7 EPH receptor A7 2045 ENSG00000135333
22  ENSG00000058866 NA DGKG diacylglycerol kinase, gamma 90kDa 1608 ENSG00000058866
23  ENSG00000166819 NA PLIN1 perilipin 1 5346 ENSG00000166819
24  ENSG00000130173 NA C19orf80 chromosome 19 open reading frame 80 55908 ENSG00000130173
25  ENSG00000112559 NA MDFI MyoD family inhibitor 4188 ENSG00000112559


Database:Transcription Target       Name:hsa_TGANTCA_V$AP1_C       ID:DB_ID:2402
C=1104; O=15; E=3.33; R=4.51; rawP=1.32e-06; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138207 NA RBP4 retinol binding protein 4, plasma 5950 ENSG00000138207
2  ENSG00000112245 NA PTP4A1 protein tyrosine phosphatase type IVA, member 1 7803 ENSG00000112245
3  ENSG00000070193 NA FGF10 fibroblast growth factor 10 2255 ENSG00000070193
4  ENSG00000123360 NA PDE1B phosphodiesterase 1B, calmodulin-dependent 5153 ENSG00000123360
5  ENSG00000149573 NA MPZL2 myelin protein zero-like 2 10205 ENSG00000149573
6  ENSG00000172137 NA CALB2 calbindin 2 794 ENSG00000172137
7  ENSG00000170525 NA PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 5209 ENSG00000170525
8  ENSG00000145824 NA CXCL14 chemokine (C-X-C motif) ligand 14 9547 ENSG00000145824
9  ENSG00000006128 NA TAC1 tachykinin, precursor 1 6863 ENSG00000006128
10  ENSG00000187288 NA CIDEC cell death-inducing DFFA-like effector c 63924 ENSG00000187288
11  ENSG00000168398 NA BDKRB2 bradykinin receptor B2 624 ENSG00000168398
12  ENSG00000127241 NA MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 5648 ENSG00000127241
13  ENSG00000105227 NA PRX periaxin 57716 ENSG00000105227
14  ENSG00000112559 NA MDFI MyoD family inhibitor 4188 ENSG00000112559
15  ENSG00000170323 NA FABP4 fatty acid binding protein 4, adipocyte 2167 ENSG00000170323


Database:Transcription Target       Name:hsa_CTTTGA_V$LEF1_Q2       ID:DB_ID:2427
C=1208; O=15; E=3.64; R=4.12; rawP=3.94e-06; adjP=0.0003
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000131771 NA PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 84152 ENSG00000131771
2  ENSG00000168490 NA PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 9796 ENSG00000168490
3  ENSG00000105926 NA MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) 51678 ENSG00000105926
4  ENSG00000070193 NA FGF10 fibroblast growth factor 10 2255 ENSG00000070193
5  ENSG00000132170 NA PPARG peroxisome proliferator-activated receptor gamma 5468 ENSG00000132170
6  ENSG00000145423 NA SFRP2 secreted frizzled-related protein 2 6423 ENSG00000145423
7  ENSG00000175426 NA PCSK1 proprotein convertase subtilisin/kexin type 1 5122 ENSG00000175426
8  ENSG00000076716 NA GPC4 glypican 4 2239 ENSG00000076716
9  ENSG00000122756 NA CNTFR ciliary neurotrophic factor receptor 1271 ENSG00000122756
10  ENSG00000182782 NA HCAR2 hydroxycarboxylic acid receptor 2 338442 ENSG00000182782
11  ENSG00000135333 NA EPHA7 EPH receptor A7 2045 ENSG00000135333
12  ENSG00000197696 NA NMB neuromedin B 4828 ENSG00000197696
13  ENSG00000091513 NA TF transferrin 7018 ENSG00000091513
14  ENSG00000170323 NA FABP4 fatty acid binding protein 4, adipocyte 2167 ENSG00000170323
15  ENSG00000168792 NA ABHD15 abhydrolase domain containing 15 116236 ENSG00000168792


Database:Transcription Target       Name:hsa_V$CEBPB_01       ID:DB_ID:1916
C=258; O=7; E=0.78; R=9.00; rawP=1.43e-05; adjP=0.0005
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000157617 NA C2CD2 C2 calcium-dependent domain containing 2 25966 ENSG00000157617
2  ENSG00000125730 NA C3 complement component 3 718 ENSG00000125730
3  ENSG00000123360 NA PDE1B phosphodiesterase 1B, calmodulin-dependent 5153 ENSG00000123360
4  ENSG00000135333 NA EPHA7 EPH receptor A7 2045 ENSG00000135333
5  ENSG00000188517 NA COL25A1 collagen, type XXV, alpha 1 84570 ENSG00000188517
6  ENSG00000133317 NA LGALS12 lectin, galactoside-binding, soluble, 12 85329 ENSG00000133317
7  ENSG00000170323 NA FABP4 fatty acid binding protein 4, adipocyte 2167 ENSG00000170323


Database:Transcription Target       Name:hsa_TGTTTGY_V$HNF3_Q6       ID:DB_ID:2423
C=733; O=11; E=2.21; R=4.98; rawP=1.48e-05; adjP=0.0005
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000092445 NA TYRO3 TYRO3 protein tyrosine kinase 7301 ENSG00000092445
2  ENSG00000065325 NA GLP2R glucagon-like peptide 2 receptor 9340 ENSG00000065325
3  ENSG00000131771 NA PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 84152 ENSG00000131771
4  ENSG00000149573 NA MPZL2 myelin protein zero-like 2 10205 ENSG00000149573
5  ENSG00000172901 NA AQPEP laeverin 206338 ENSG00000172901
6  ENSG00000182782 NA HCAR2 hydroxycarboxylic acid receptor 2 338442 ENSG00000182782
7  ENSG00000135333 NA EPHA7 EPH receptor A7 2045 ENSG00000135333
8  ENSG00000127241 NA MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 5648 ENSG00000127241
9  ENSG00000091513 NA TF transferrin 7018 ENSG00000091513
10  ENSG00000105227 NA PRX periaxin 57716 ENSG00000105227
11  ENSG00000008394 NA MGST1 microsomal glutathione S-transferase 1 4257 ENSG00000008394


Database:Transcription Target       Name:hsa_CAGGTG_V$E12_Q6       ID:DB_ID:2409
C=2450; O=21; E=7.39; R=2.84; rawP=1.41e-05; adjP=0.0005
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000092445 NA TYRO3 TYRO3 protein tyrosine kinase 7301 ENSG00000092445
2  ENSG00000159173 NA TNNI1 troponin I type 1 (skeletal, slow) 7135 ENSG00000159173
3  ENSG00000139641 NA ESYT1 extended synaptotagmin-like protein 1 23344 ENSG00000139641
4  ENSG00000186642 NA PDE2A phosphodiesterase 2A, cGMP-stimulated 5138 ENSG00000186642
5  ENSG00000120875 NA DUSP4 dual specificity phosphatase 4 1846 ENSG00000120875
6  ENSG00000176463 NA SLCO3A1 solute carrier organic anion transporter family, member 3A1 28232 ENSG00000176463
7  ENSG00000167588 NA GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2819 ENSG00000167588
8  ENSG00000177885 NA GRB2 growth factor receptor-bound protein 2 2885 ENSG00000177885
9  ENSG00000152822 NA GRM1 glutamate receptor, metabotropic 1 2911 ENSG00000152822
10  ENSG00000168490 NA PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 9796 ENSG00000168490
11  ENSG00000065325 NA GLP2R glucagon-like peptide 2 receptor 9340 ENSG00000065325
12  ENSG00000173599 NA PC pyruvate carboxylase 5091 ENSG00000173599
13  ENSG00000189337 NA KAZN kazrin, periplakin interacting protein 23254 ENSG00000189337
14  ENSG00000062282 NA DGAT2 diacylglycerol O-acyltransferase 2 84649 ENSG00000062282
15  ENSG00000124253 NA PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 5105 ENSG00000124253
16  ENSG00000185818 NA NAT8L N-acetyltransferase 8-like (GCN5-related, putative) 339983 ENSG00000185818
17  ENSG00000145824 NA CXCL14 chemokine (C-X-C motif) ligand 14 9547 ENSG00000145824
18  ENSG00000006128 NA TAC1 tachykinin, precursor 1 6863 ENSG00000006128
19  ENSG00000143867 NA OSR1 odd-skipped related 1 (Drosophila) 130497 ENSG00000143867
20  ENSG00000058866 NA DGKG diacylglycerol kinase, gamma 90kDa 1608 ENSG00000058866
21  ENSG00000127241 NA MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 5648 ENSG00000127241


Database:Transcription Target       Name:hsa_V$PAX2_02       ID:DB_ID:2139
C=255; O=7; E=0.77; R=9.11; rawP=1.32e-05; adjP=0.0005
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000170525 NA PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 5209 ENSG00000170525
2  ENSG00000105926 NA MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) 51678 ENSG00000105926
3  ENSG00000143867 NA OSR1 odd-skipped related 1 (Drosophila) 130497 ENSG00000143867
4  ENSG00000120875 NA DUSP4 dual specificity phosphatase 4 1846 ENSG00000120875
5  ENSG00000092621 NA PHGDH phosphoglycerate dehydrogenase 26227 ENSG00000092621
6  ENSG00000132170 NA PPARG peroxisome proliferator-activated receptor gamma 5468 ENSG00000132170
7  ENSG00000176463 NA SLCO3A1 solute carrier organic anion transporter family, member 3A1 28232 ENSG00000176463


Database:Transcription Target       Name:hsa_V$PPAR_DR1_Q2       ID:DB_ID:2248
C=257; O=7; E=0.77; R=9.04; rawP=1.39e-05; adjP=0.0005
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000145824 NA CXCL14 chemokine (C-X-C motif) ligand 14 9547 ENSG00000145824
2  ENSG00000168490 NA PHYHIP phytanoyl-CoA 2-hydroxylase interacting protein 9796 ENSG00000168490
3  ENSG00000176720 NA BOK BCL2-related ovarian killer 666 ENSG00000176720
4  ENSG00000166819 NA PLIN1 perilipin 1 5346 ENSG00000166819
5  ENSG00000130173 NA C19orf80 chromosome 19 open reading frame 80 55908 ENSG00000130173
6  ENSG00000100075 NA SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 6576 ENSG00000100075
7  ENSG00000167588 NA GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2819 ENSG00000167588


Database:Transcription Target       Name:hsa_V$HNF4_01       ID:DB_ID:1938
C=264; O=7; E=0.80; R=8.80; rawP=1.66e-05; adjP=0.0005
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000122756 NA CNTFR ciliary neurotrophic factor receptor 1271 ENSG00000122756
2  ENSG00000158571 NA PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 5207 ENSG00000158571
3  ENSG00000070193 NA FGF10 fibroblast growth factor 10 2255 ENSG00000070193
4  ENSG00000132170 NA PPARG peroxisome proliferator-activated receptor gamma 5468 ENSG00000132170
5  ENSG00000100075 NA SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 6576 ENSG00000100075
6  ENSG00000124253 NA PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 5105 ENSG00000124253
7  ENSG00000167588 NA GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2819 ENSG00000167588




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).